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Anti-Human SGSM3 Polyclonal Antibody

  • Cat. No.:RB9THD154014
  • Price:Negotiable
  • Clicks:340

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetMAP, Merlin-associated protein, RABGAPLP, RUN and TBC1 domain-containing protein 3, RUTBC3, Rab-GTPase-activating protein-like protein, RabGAPLP, SGSM3, Small G protein signaling modulator 3
ImmunogenE. coli - derived recombinant Human SGSM3 (Met1-Gly382).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ96HU1
Background

Small G protein signaling modulator 3 (SGSM3) is a ~85 kDa protein. GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells.

1. Haas, AK. et al. (2005) Nature cell biology 7, 887-93. PMID: 16086013
2. Fuchs, E. et al. (2007) The Journal of cell biology 177, 1133-43. PMID: 17562788
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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