Anti-Human SGSM3 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	MAP, Merlin-associated protein, RABGAPLP, RUN and TBC1 domain-containing protein 3, RUTBC3, Rab-GTPase-activating protein-like protein, RabGAPLP, SGSM3, Small G protein signaling modulator 3
Immunogen	E. coli - derived recombinant Human SGSM3 (Met1-Gly382).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q96HU1
Background	Small G protein signaling modulator 3 (SGSM3) is a ~85 kDa protein. GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells. 1. Haas, AK. et al. (2005) Nature cell biology 7, 887-93. PMID: 16086013 2. Fuchs, E. et al. (2007) The Journal of cell biology 177, 1133-43. PMID: 17562788
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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