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Anti-Human MRPL12 Polyclonal Antibody

  • Cat. No.:RB9THC170014
  • Price:Negotiable
  • Clicks:253

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
Target39S ribosomal protein L12, mitochondrial; L12mt; MRP-L12; 5c5-2; Mitochondrial large ribosomal subunit protein bL12m; MRPL12; MRPL7; RPML12
ImmunogenE. coli - derived recombinant Human MRPL12 (His129-Glu198).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP52815
Background

Large ribosomal subunit protein bL12m (MRPL12) is a ~21 kDa protein. As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability.

1. Serre, V. et al. (2013) Biochimica et biophysica acta 1832, 1304-12. PMID: 23603806
2. Surovtseva, YV. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 17921-6. PMID: 22003127
3. Nouws, J. et al. (2016) The Journal of biological chemistry 291, 989-97. PMID: 26586915
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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