| Form | Liquid |
|---|---|
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA |
| Species Reactivity | Homo sapiens (Human) |
| Target | EC:3.4.21.59, TPS1, TPS2, TPSAB1, TPSB1, Tryptase I, Tryptase alpha-1, Tryptase alpha/beta-1, Tryptase-1 |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Accession Number | Q15661 |
| Background | Tryptase alpha/beta-1 (β-tryptase/TPSAB1) is a ~30 kDa protein. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. 1. Jackson, NE. et al. (2008) The Journal of biological chemistry 283, 34178-87. PMID: 18854315 |
| Note | For research use only |