Anti-Human CDw210b/IL10RB Polyclonal Antibody
- Cat. No.：RB9THC339014
- Price：Negotiable
- Clicks：242
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CDw210b, CRF2-4, CRFB4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, D21S58, D21S66, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, |
| Immunogen | E. coli - derived recombinant Human CDw210b/IL10RB (Leu87-Ala243). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping Condition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q08334 |
| Observed Molecular Weight | 42 kDa |
| Background | Interleukin-10 receptor subunit beta (CDw210b/IL10RB) is a ~36 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. |
| Note | For research use only |
Related Products: