| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | EH domain-containing protein 3, EHD2, EHD3, PAST homolog 3, PAST3 |
| Immunogen | E. coli - derived recombinant Human EHD3 (Thr20-Ser402). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9NZN3 |
| Background | EH domain-containing protein 3 (EHD3) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. 1. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250 2. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528 3. Naslavsky, N. et al. (2006) Molecular biology of the cell 17, 163-77. PMID: 16251358 4. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914 5. Naslavsky, N. et al. (2009) Journal of cell science 122, 389-400. PMID: 19139087 6. Waxmonsky, NC. et al. (2013) Journal of cell science 126, 3593-601. PMID: 23781025 7. Kotowski, SJ. et al. (2011) Neuron 71, 278-90. PMID: 21791287 8. Gudmundsson, H. et al. (2010) Circulation research 107, 84-95. PMID: 20489164 |
| Note | For research use only |
| Product Name | Clicks |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7386 |
| 人触珠蛋白单克隆抗体 | 7586 |
| 贾第鞭毛虫单克隆抗体 | 7285 |
| 阿米巴单克隆抗体 | 7740 |
| 胃蛋白酶单克隆抗体 | 7316 |
| 胃蛋白酶原II单克隆抗体 | 7400 |
| 胃蛋白酶原I单克隆抗体 | 7213 |
| 艰难梭菌毒素A单克隆抗体 | 7363 |
| 艰难梭菌毒素B单克隆抗体 | 7585 |
| 艰难梭菌GDH单克隆抗体 | 7571 |
| 诺如病毒单克隆抗体 | 7149 |
| 伤寒沙门氏菌单克隆抗体 | 7274 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6753 |
| 幽门螺杆菌单克隆抗体 | 7232 |
| 钙卫蛋白单克隆抗体 | 7114 |
| 乳铁蛋白单克隆抗体 | 7385 |
| 转铁蛋白单克隆抗体 | 7371 |
| 血红蛋白单克隆抗体 | 7171 |
| 腺病毒单克隆抗体 | 7348 |
| 轮状病毒单克隆抗体 | 7621 |