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Anti-Human EHD3 Polyclonal Antibody

  • Cat. No.:RB9THC245014
  • Price:Negotiable
  • Clicks:490

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Human, Mouse
TargetEH domain-containing protein 3, EHD2, EHD3, PAST homolog 3, PAST3
ImmunogenE. coli - derived recombinant Human EHD3 (Thr20-Ser402).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9NZN3
Background

EH domain-containing protein 3 (EHD3) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport.

1. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250
2. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528
3. Naslavsky, N. et al. (2006) Molecular biology of the cell 17, 163-77. PMID: 16251358
4. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914
5. Naslavsky, N. et al. (2009) Journal of cell science 122, 389-400. PMID: 19139087
6. Waxmonsky, NC. et al. (2013) Journal of cell science 126, 3593-601. PMID: 23781025
7. Kotowski, SJ. et al. (2011) Neuron 71, 278-90. PMID: 21791287
8. Gudmundsson, H. et al. (2010) Circulation research 107, 84-95. PMID: 20489164
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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