| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | EH domain-containing protein 3, EHD2, EHD3, PAST homolog 3, PAST3 |
| Immunogen | E. coli - derived recombinant Human EHD3 (Thr20-Ser402). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9NZN3 |
| Background | EH domain-containing protein 3 (EHD3) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. 1. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250 2. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528 3. Naslavsky, N. et al. (2006) Molecular biology of the cell 17, 163-77. PMID: 16251358 4. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914 5. Naslavsky, N. et al. (2009) Journal of cell science 122, 389-400. PMID: 19139087 6. Waxmonsky, NC. et al. (2013) Journal of cell science 126, 3593-601. PMID: 23781025 7. Kotowski, SJ. et al. (2011) Neuron 71, 278-90. PMID: 21791287 8. Gudmundsson, H. et al. (2010) Circulation research 107, 84-95. PMID: 20489164 |
| Note | For research use only |
| Product Name | Clicks |
|---|---|
| 氯丙嗪单抗 | 5739 |
| 西马特罗单抗 | 5526 |
| 孕酮单抗 | 5824 |
| 氯霉素(CAP)单抗 | 5783 |
| 红霉素单抗 | 5746 |
| 地克珠利单抗 | 5527 |
| 无色孔雀石绿(LMG)单抗 | 5833 |
| 雌二醇单抗 | 5437 |
| 孔雀石绿(MG)单抗 | 5936 |
| 双酚A单抗 | 5635 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5657 |
| 己烯雌酚单抗 | 5594 |
| 莱克多巴胺(RAC)单抗 | 5663 |
| 林可霉素单抗 | 5825 |
| 抗青霉素受体单抗 | 5622 |
| 大观霉素单抗 | 5677 |
| 克伦特罗(CL)单抗 | 5808 |
| 沙拉沙星单抗(2H4) | 5766 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5828 |
| 磺胺类SAS单抗 | 5784 |