| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | EH domain-containing protein 3, EHD2, EHD3, PAST homolog 3, PAST3 |
| Immunogen | E. coli - derived recombinant Human EHD3 (Thr20-Ser402). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9NZN3 |
| Background | EH domain-containing protein 3 (EHD3) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. 1. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250 2. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528 3. Naslavsky, N. et al. (2006) Molecular biology of the cell 17, 163-77. PMID: 16251358 4. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914 5. Naslavsky, N. et al. (2009) Journal of cell science 122, 389-400. PMID: 19139087 6. Waxmonsky, NC. et al. (2013) Journal of cell science 126, 3593-601. PMID: 23781025 7. Kotowski, SJ. et al. (2011) Neuron 71, 278-90. PMID: 21791287 8. Gudmundsson, H. et al. (2010) Circulation research 107, 84-95. PMID: 20489164 |
| Note | For research use only |
| Product Name | Clicks |
|---|---|
| 炔诺酮单抗 | 5605 |
| 磺胺氯吡嗪单抗 | 5580 |
| 呋喃苯烯酸钠单抗 | 5525 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5405 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5295 |
| 磺胺喹恶啉单抗 | 5568 |
| 苯丙酸诺龙单抗 | 5400 |
| 司帕沙星单抗 | 5307 |
| 妥布霉素单抗 | 5474 |
| 甲氧氯普胺单抗 | 5388 |
| 莫能菌素单抗 | 5506 |
| 多粘菌素B(粘菌素)单抗 | 5847 |
| 磺胺类单抗 | 5607 |
| 托灭酸(托芬那酸)单抗 | 5411 |
| 卡洛芬单抗 | 5394 |
| 喹乙醇代谢物MQCA单抗 | 5462 |
| 氟尼辛单抗 | 5379 |
| 磺胺二甲嘧啶(SM2)单抗 | 5268 |
| 诺龙(19-去甲睾酮)单抗 | 5372 |
| 阿苯达唑-2-氨基砜单抗 | 5319 |