| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | G antigen family C member 1, GAGEC1, P antigen family member 4, PAGE-1, PAGE-4, PAGE4 |
| Immunogen | E. coli - derived recombinant Human PAGE4 (Ser2-Pro102). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O60829 |
| Background | P antigen family member 4 (PAGE4) is a ~11 kDa protein. Intrinsically disordered protein that potentiates the transcriptional activator activity of JUN. Protects cells from stress-induced apoptosis by inhibiting reactive oxygen species (ROS) production and via regulation of the MAPK signaling pathway. 1. Rajagopalan, K. et al. (2014) Biochimica et biophysica acta 1842, 154-63. PMID: 24263171 2. Kulkarni, P. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E2644-E2653. PMID: 28289210 3. Zeng, Y. et al. (2011) The Journal of biological chemistry 286, 13985-94. PMID: 21357425 4. Zeng, Y. et al. (2013) American journal of clinical and experimental urology 1, 39-52. PMID: 25374899 5. Lv, C. et al. (2019) Journal of experimental & clinical cancer research : CR 38, 24. PMID: 30658679 |
| Note | For research use only |