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Anti-Human RDH16 Polyclonal Antibody

  • Cat. No.:RB9THC958014
  • Price:Negotiable
  • Clicks:253

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetEC:1.1.1.105, EC:1.1.1.209, EC:1.1.1.315, EC:1.1.1.53, Human epidermal retinol dehydrogenase, Microsomal NAD(+)-dependent retinol dehydrogenase 4, RDH16, RODH4, Retinol dehydrogenase 16, RoDH-4, SDR9C
ImmunogenE. coli - derived recombinant Human RDH16 (Arg28-Lys288).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberO75452
Background

Retinol dehydrogenase 16 (RDH16) is a ~35 kDa protein. Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Also oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione.

1. Jurukovski, V. et al. (1999) Molecular genetics and metabolism 67, 62-73. PMID: 10329026
2. Lapshina, EA. et al. (2003) Biochemistry 42, 776-84. PMID: 12534290
3. Gough, WH. et al. (1998) The Journal of biological chemistry 273, 19778-85. PMID: 9677409
4. Fiandalo, MV. et al. (2018) Oncotarget 9, 11227-11242. PMID: 29541409
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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