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Anti-Human RGS6 Polyclonal Antibody

  • Cat. No.:RB9THD046014
  • Price:Negotiable
  • Clicks:422

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse
TargetRGS6, Regulator of G-protein signaling 6, S914
ImmunogenE. coli - derived recombinant Human RGS6 (Ser19-Gly235).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP49758
Background

Regulator of G-protein signaling 6 (RGS6) is a ~54 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity.

1. Posner, BA. et al. (1999) The Journal of biological chemistry 274, 31087-93. PMID: 10521509
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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