| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | RGS6, Regulator of G-protein signaling 6, S914 |
| Immunogen | E. coli - derived recombinant Human RGS6 (Ser19-Gly235). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P49758 |
| Background | Regulator of G-protein signaling 6 (RGS6) is a ~54 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity. 1. Posner, BA. et al. (1999) The Journal of biological chemistry 274, 31087-93. PMID: 10521509 |
| Note | For research use only |