Anti-Human IL1RAPL1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Human, Mouse
Target	EC:3.2.2.6, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, IL1RAPL1, Interleukin-1 receptor accessory protein-like 1, OPHN4, Oligophrenin-4, TIGIRR-2, Three immunoglobulin domain-containing IL-1 receptor-related
Immunogen	E. coli - derived recombinant Human IL1RAPL1 (Thr32-Arg352).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q9NZN1
Background	Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a ~79 kDa protein. May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD. 1. Bahi, N. et al. (2003) Human molecular genetics 12, 1415-25. PMID: 12783849 2. Khan, JA. et al. (2004) The Journal of biological chemistry 279, 31664-70. PMID: 15123616
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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