| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | EC:3.2.2.6, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, IL1RAPL1, Interleukin-1 receptor accessory protein-like 1, OPHN4, Oligophrenin-4, TIGIRR-2, Three immunoglobulin domain-containing IL-1 receptor-related |
| Immunogen | E. coli - derived recombinant Human IL1RAPL1 (Thr32-Arg352). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9NZN1 |
| Background | Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a ~79 kDa protein. May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD. 1. Bahi, N. et al. (2003) Human molecular genetics 12, 1415-25. PMID: 12783849 2. Khan, JA. et al. (2004) The Journal of biological chemistry 279, 31664-70. PMID: 15123616 |
| Note | For research use only |