Anti-Human ZNF827 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	ZNF827, Zinc finger protein 827
Immunogen	E. coli - derived recombinant Human ZNF827 (Ser809-Gly954).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q17R98
Background	Zinc finger protein 827 (ZNF827) is a ~119 kDa protein. As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance. 1. Hollensen, AK. et al. (2020) eLife 9. PMID: 33174841 2. Conomos, D. et al. (2014) Nature structural & molecular biology 21, 760-70. PMID: 25150861
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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