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Anti-Human ZNF827 Polyclonal Antibody

  • Cat. No.:RB9THD261014
  • Price:Negotiable
  • Clicks:284

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetZNF827, Zinc finger protein 827
ImmunogenE. coli - derived recombinant Human ZNF827 (Ser809-Gly954).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ17R98
Background

Zinc finger protein 827 (ZNF827) is a ~119 kDa protein. As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance.

1. Hollensen, AK. et al. (2020) eLife 9. PMID: 33174841
2. Conomos, D. et al. (2014) Nature structural & molecular biology 21, 760-70. PMID: 25150861
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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