| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | ZNF827, Zinc finger protein 827 |
| Immunogen | E. coli - derived recombinant Human ZNF827 (Ser809-Gly954). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q17R98 |
| Background | Zinc finger protein 827 (ZNF827) is a ~119 kDa protein. As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance. 1. Hollensen, AK. et al. (2020) eLife 9. PMID: 33174841 2. Conomos, D. et al. (2014) Nature structural & molecular biology 21, 760-70. PMID: 25150861 |
| Note | For research use only |