Anti-Human UTP25 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	C1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component
Immunogen	E. coli - derived recombinant Human UTP25 (Asn180-Asn561).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q68CQ4
Background	U3 small nucleolar RNA-associated protein 25 homolog (UTP25) is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53. 1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851 2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945 3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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