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Anti-Human UTP25 Polyclonal Antibody

  • Cat. No.:RB9THD313014
  • Price:Negotiable
  • Clicks:412

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetC1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component
ImmunogenE. coli - derived recombinant Human UTP25 (Asn180-Asn561).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ68CQ4
Background

U3 small nucleolar RNA-associated protein 25 homolog (UTP25) is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53.

1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851
2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945
3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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