Anti-Human SVIL Polyclonal Antibody
- Cat. No.：RB9THF800014
- Price：Negotiable
- Clicks：282
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | Archvillin, SVIL, Supervillin, p205/p250 |
| Immunogen | E. coli - derived recombinant Human SVIL (Met1444-Lys1678). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O95425 |
| Background | Supervillin (SVIL) is a ~247 kDa protein. Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. 1. Oh, SW. et al. (2003) Journal of cell science 116, 2261-75. PMID: 12711699 2. Crowley, JL. et al. (2009) Molecular biology of the cell 20, 948-62. PMID: 19109420 3. Laurent, B. et al. (2015) Molecular cell 57, 957-970. PMID: 25684206 |
| Note | For research use only |
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