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Anti-Human SMYD3 Polyclonal Antibody

  • Cat. No.:RB9THP320024
  • Price:Negotiable
  • Clicks:178

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetEC:2.1.1.354, Histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, SMYD3, ZMYND1, ZNFN3A1, Zinc finger MYND domain-containing protein 1
ImmunogenE. coli - derived recombinant Human SMYD3 (Met1-Ser428).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9H7B4
Background

Histone-lysine N-methyltransferase SMYD3 is a ~49 kDa protein. Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys-5' of histone H4. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.

1. Hamamoto, R. et al. (2004) Nature cell biology 6, 731-40. PMID: 15235609
2. Van Aller, GS. et al. (2012) Epigenetics 7, 340-3. PMID: 22419068
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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