Anti-Human CAVIN1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF, Polymerase I and transcript release factor
Immunogen	E. coli - derived recombinant Human CAVIN1 (Leu43-Val153).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q6NZI2
Background	Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. 1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712 2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225 3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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