| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Mouse, Human |
| Target | CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF, Polymerase I and transcript release factor |
| Immunogen | E. coli - derived recombinant Human CAVIN1 (Leu43-Val153). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q6NZI2 |
| Background | Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. 1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712 2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225 3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876 |
| Note | For research use only |