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Anti-Human CAVIN1 Polyclonal Antibody

  • Cat. No.:RB9THP645024
  • Price:Negotiable
  • Clicks:641

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetCAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF, Polymerase I and transcript release factor
ImmunogenE. coli - derived recombinant Human CAVIN1 (Leu43-Val153).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ6NZI2
Background

Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop.

1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712
2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225
3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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