| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mycoplasma pneumoniae |
| Target | Cytoskeletal protein P41, Wheel complex protein P41 |
| Immunogen | E. coli - derived recombinant Mycoplasma pneumoniae Wheel complex protein P41 (Met1-Gln220). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P75470 |
| Background | Wheel complex protein P41 is a ~40 kDa protein. Stably anchors the attachment organelle to the cell body and for their spatial positioning. Required for stable accumulation of P28 (also called HMW2-s, a short protein produced by upstream MPN_310). Required for correct localization of P24. Ectopic expression of P41 restores gliding velocity but not gliding frequency to a P41-P24 disruption, attachment organelles do not initiate as frequently as in wild-type; inclusion of P24 restores a wild-type phenotype. May play a role in attachment organelle initiation and its coordination with the cell cycle (Probable). 1. Hasselbring, BM. et al. (2007) Molecular microbiology 63, 44-53. PMID: 17163973 2. Hasselbring, BM. et al. (2007) Journal of bacteriology 189, 7442-9. PMID: 17693502 3. Nakane, D. et al. (2015) PLoS pathogens 11, e1005299. PMID: 26633540 |
| Note | For research use only |
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