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Anti-Mycoplasma pneumoniae Wheel complex protein P41 Polyclonal Antibody

  • Cat. No.:RB9TJN180034
  • Price:Negotiable
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Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMycoplasma pneumoniae
TargetCytoskeletal protein P41, Wheel complex protein P41
ImmunogenE. coli - derived recombinant Mycoplasma pneumoniae Wheel complex protein P41 (Met1-Gln220).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP75470
Background

Wheel complex protein P41 is a ~40 kDa protein. Stably anchors the attachment organelle to the cell body and for their spatial positioning. Required for stable accumulation of P28 (also called HMW2-s, a short protein produced by upstream MPN_310). Required for correct localization of P24. Ectopic expression of P41 restores gliding velocity but not gliding frequency to a P41-P24 disruption, attachment organelles do not initiate as frequently as in wild-type; inclusion of P24 restores a wild-type phenotype. May play a role in attachment organelle initiation and its coordination with the cell cycle (Probable).

1. Hasselbring, BM. et al. (2007) Molecular microbiology 63, 44-53. PMID: 17163973
2. Hasselbring, BM. et al. (2007) Journal of bacteriology 189, 7442-9. PMID: 17693502
3. Nakane, D. et al. (2015) PLoS pathogens 11, e1005299. PMID: 26633540
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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