Anti-Mycoplasma pneumoniae Wheel complex protein P41 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mycoplasma pneumoniae
Target	Cytoskeletal protein P41, Wheel complex protein P41
Immunogen	E. coli - derived recombinant Mycoplasma pneumoniae Wheel complex protein P41 (Met1-Gln220).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P75470
Background	Wheel complex protein P41 is a ~40 kDa protein. Stably anchors the attachment organelle to the cell body and for their spatial positioning. Required for stable accumulation of P28 (also called HMW2-s, a short protein produced by upstream MPN_310). Required for correct localization of P24. Ectopic expression of P41 restores gliding velocity but not gliding frequency to a P41-P24 disruption, attachment organelles do not initiate as frequently as in wild-type; inclusion of P24 restores a wild-type phenotype. May play a role in attachment organelle initiation and its coordination with the cell cycle (Probable). 1. Hasselbring, BM. et al. (2007) Molecular microbiology 63, 44-53. PMID: 17163973 2. Hasselbring, BM. et al. (2007) Journal of bacteriology 189, 7442-9. PMID: 17693502 3. Nakane, D. et al. (2015) PLoS pathogens 11, e1005299. PMID: 26633540
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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