Anti-Human CEMIP Polyclonal Antibody
- Cat. No.：RB9THV103044
- Price：Negotiable
- Clicks：317
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CEMIP, Cell migration-inducing and hyaluronan-binding protein, EC:3.2.1.35, HYBID, Hyaluronan binding protein involved in hyaluronan depolymerization, KIAA1199 |
| Immunogen | E. coli - derived recombinant Human CEMIP (Thr31-Ala386). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q8WUJ3 |
| Background | Cell migration-inducing and hyaluronan-binding protein (CEMIP) is a ~152 kDa protein. Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. |
| Note | For research use only |
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