Anti-HHV-8 vIL-6/K2 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human herpesvirus 8 type P
Target	K2, Viral interleukin-6 homolog, vIL-6
Immunogen	E. coli - derived recombinant HHV-8 vIL-6/K2 (Lys23-Lys204).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q2HRC7
Background	Viral interleukin-6 homolog (vIL-6/K2) is a ~23 kDa protein. Initiates signal transduction through binding to interleukin-6 receptor subunit beta IL6ST, independently of the cognate IL6 receptor IL6R. In infected primary effusion lymphoma cells, promotes proliferation of cells, protects them from apoptosis, and promotes immune evasion of interferon activity. Also drives blood to lymphatic endothelial cell differentiation.
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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