| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human herpesvirus 8 type P |
| Target | K2, Viral interleukin-6 homolog, vIL-6 |
| Immunogen | E. coli - derived recombinant HHV-8 vIL-6/K2 (Lys23-Lys204). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q2HRC7 |
| Background | Viral interleukin-6 homolog (vIL-6/K2) is a ~23 kDa protein. Initiates signal transduction through binding to interleukin-6 receptor subunit beta IL6ST, independently of the cognate IL6 receptor IL6R. In infected primary effusion lymphoma cells, promotes proliferation of cells, protects them from apoptosis, and promotes immune evasion of interferon activity. Also drives blood to lymphatic endothelial cell differentiation. |
| Note | For research use only |