Anti-HHV-5/HCMV UL130 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human cytomegalovirus
Target	Envelope glycoprotein UL130, UL130
Immunogen	E. coli - derived recombinant HHV-5/HCMV UL130 (Ser26-Val214).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	F5HCP3
Background	Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. 1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555 2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586 3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665 4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

Related Products: