Anti-HHV-5/HCMV UL130 Polyclonal Antibody
- Cat. No.：RB9TVK480014
- Price：Negotiable
- Clicks：450
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human cytomegalovirus |
| Target | Envelope glycoprotein UL130, UL130 |
| Immunogen | E. coli - derived recombinant HHV-5/HCMV UL130 (Ser26-Val214). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | F5HCP3 |
| Background | Envelope glycoprotein UL130 is a ~24 kDa protein. Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. 1. Ryckman, BJ. et al. (2008) Journal of virology 82, 60-70. PMID: 17942555 2. Nogalski, MT. et al. (2013) PLoS pathogens 9, e1003463. PMID: 23853586 3. Chandramouli, S. et al. (2017) Science immunology 2. PMID: 28783665 4. Martinez-Martin, N. et al. (2018) Cell 174, 1158-1171.e19. PMID: 30057110 |
| Note | For research use only |
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