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Recombinant Mouse TFF3 (C-6His)

  • Cat. No.:EPT168
  • Price:Negotiable
  • Clicks:1052

Product Detail

Basic Information

Size50ug
Expression HostHuman Cells
TagC-6His

Physical Properties

Molecular Weight7.3 KDa
Apparent Molecular Weight11 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
PurityGreater than 95% as determined by reducing SDS-PAGE.

Activity & Endotoxin

Endotoxin LevelLess than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Storage & Shipping

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Detailed Description

BackgroundTrefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3). They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfide bonds. They are stable secretory proteins expressed in gastrointestinal mucosa. Trefoil Factor 3(TFF3) is involved in the maintenance and repair of the intestinal mucosa. TFF3 promotes the mobility of epithelial cells in healing processes (motogen).
For Research Use Only. Not for Diagnostic Procedures.

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