Recombinant Human OX40L (C-mFc)
- Cat. No.：EPT015
- Price：USD $ 1,260.00
- Clicks：1375
Product Detail
Basic Information
| Size | 10ug |
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| Expression Host | Human Cells |
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| Tag | C-mFc |
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Physical Properties
| Molecular Weight | 42.2 KDa |
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| Apparent Molecular Weight | 50-70 KDa, reducing conditions |
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| Form | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
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| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
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Activity & Endotoxin
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
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| Activity | Immobilized Human OX40-Fc(Cat#CK58) at 8μg/ml (100 μl/well)can bind Human OX40L-mFc(Cat#CW25).The ED50 of Human OX40L-mFc(Cat#CW25)is 18.54 ng/ml. |
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Storage & Shipping
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
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| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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| Shipping Condition | The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below. |
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Detailed Description
| Background | Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40 (CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional, it has been found association with systemic lupus erythematosus, no association with occurrence of atherosclerosis. |
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