Anti-Mouse MAdCAM-1 Recombinant Antibody
- Cat. No.：RB9TMC589023
- Price：Negotiable
- Clicks：166
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | IP, WP, Block, FCM, IHC |
| Species Reactivity | Mus musculus (Mouse) |
| Target | MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1 |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Accession Number | Q61826 |
| Background | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
| Note | For research use only |
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