| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | Serine/threonine-protein kinase Nek1; 2.7.11.1; Never in mitosis A-related kinase 1; NimA-related protein kinase 1; Renal carcinoma antigen NY-REN-55; NEK1; KIAA1901 |
| Immunogen | E. coli - derived recombinant Human NEK1 (Cys1177-Glu1258). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q96PY6 |
| Background | Serine/threonine-protein kinase Nek1 is a ~142 kDa protein. Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis. Involved in cilium assembly. 1. Chen, Y. et al. (2010) Biochemical and biophysical research communications 394, 798-803. PMID: 20230784 2. Thiel, C. et al. (2011) American journal of human genetics 88, 106-14. PMID: 21211617 |
| Note | For research use only |
| Product Name | Clicks |
|---|---|
| 炔诺酮单抗 | 5420 |
| 磺胺氯吡嗪单抗 | 5431 |
| 呋喃苯烯酸钠单抗 | 5329 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5248 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5145 |
| 磺胺喹恶啉单抗 | 5370 |
| 苯丙酸诺龙单抗 | 5265 |
| 司帕沙星单抗 | 5101 |
| 妥布霉素单抗 | 5325 |
| 甲氧氯普胺单抗 | 5228 |
| 莫能菌素单抗 | 5328 |
| 多粘菌素B(粘菌素)单抗 | 5661 |
| 磺胺类单抗 | 5427 |
| 托灭酸(托芬那酸)单抗 | 5247 |
| 卡洛芬单抗 | 5219 |
| 喹乙醇代谢物MQCA单抗 | 5330 |
| 氟尼辛单抗 | 5182 |
| 磺胺二甲嘧啶(SM2)单抗 | 5084 |
| 诺龙(19-去甲睾酮)单抗 | 5223 |
| 阿苯达唑-2-氨基砜单抗 | 5172 |