Anti-Human SOX10 Polyclonal Antibody
- Cat. No.：RB9THX928024
- Price：Negotiable
- Clicks：650
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | Transcription factor SOX-10; SOX10 |
| Immunogen | E. coli - derived recombinant Human SOX10 (Lys67-Asp170). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P56693 |
| Background | Transcription factor SOX-10 (SOX10) is a ~49 kDa protein. Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter. 1. Zhang, H. et al. (2012) Human genetics 131, 491-503. PMID: 21965087 |
| Note | For research use only |
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