| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | Ceruloplasmin; 1.16.3.1; Ferroxidase; CP |
| Immunogen | E. coli - derived recombinant Human CP (Asp789-Gly1065). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P00450 |
| Background | Ceruloplasmin (CP) is a ~122 kDa protein. Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. 1. Hochstrasser, H. et al. (2005) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19, 1851-3. PMID: 16150804 2. Stoj, C. et al. (2003) FEBS letters 554, 422-6. PMID: 14623105 3. Young, SN. et al. (1972) The Biochemical journal 129, 273-83. PMID: 4643313 4. Osaki, S. et al. (1966) The Journal of biological chemistry 241, 2746-51. PMID: 5912351 5. Park, YS. et al. (1999) FEBS letters 458, 133-6. PMID: 10481051 6. Shiva, S. et al. (2006) Nature chemical biology 2, 486-93. PMID: 16906150 |
| Note | For research use only |
| Product Name | Clicks |
|---|---|
| 倍硫磷单抗 | 6378 |
| 多菌灵/阿苯达唑二合一单抗 | 6416 |
| 三氯噻嗪单抗 | 6505 |
| 吡唑醚菌酯单抗 | 6601 |
| 烯酰吗啉单抗 | 6482 |
| 抑霉唑单抗 | 6240 |
| 恶醚唑(苯醚甲环唑)单抗 | 6488 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6409 |
| 辛硫磷单抗 | 6442 |
| 多效唑单抗 | 6345 |
| 对硫磷单抗 | 6603 |
| 丙溴磷单抗 | 6573 |
| 戊唑醇单抗 | 6528 |
| 莠去津单抗 | 6460 |
| 灭蝇胺单抗 | 6151 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6477 |
| 2.4-二氯苯氧乙酸单抗 | 6283 |
| 甲基对硫磷单抗 | 6355 |
| 左旋咪唑单抗 | 6354 |
| 三唑磷单抗 | 6486 |