Anti-G protein/Gαβγ Recombinant Antibody
- Cat. No.：RB9THX948023
- Price：Negotiable
- Clicks：455
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Clonality | Monoclonal |
| Isotype | scFv-His |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | Crystallography, Cryo-EM |
| Species Reactivity | Homo sapiens (Human) |
| Target | Adenylate cyclase-stimulating G alpha protein, EC:3.6.5.-, GNAS, GNAS1, GSP, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Accession Number | P63092 |
| Background | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gαβγ) is a ~45 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. 1. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 2. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 3. Thiele, S. et al. (2011) Human mutation 32, 653-60. PMID: 21488135 4. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 5. Farfel, Z. et al. (1996) The Journal of biological chemistry 271, 19653-5. PMID: 8702665 6. Warner, DR. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 4268-72. PMID: 10200251 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7331 |
| 人触珠蛋白单克隆抗体 | 7535 |
| 贾第鞭毛虫单克隆抗体 | 7222 |
| 阿米巴单克隆抗体 | 7699 |
| 胃蛋白酶单克隆抗体 | 7255 |
| 胃蛋白酶原II单克隆抗体 | 7357 |
| 胃蛋白酶原I单克隆抗体 | 7166 |
| 艰难梭菌毒素A单克隆抗体 | 7298 |
| 艰难梭菌毒素B单克隆抗体 | 7537 |
| 艰难梭菌GDH单克隆抗体 | 7506 |
| 诺如病毒单克隆抗体 | 7100 |
| 伤寒沙门氏菌单克隆抗体 | 7214 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6696 |
| 幽门螺杆菌单克隆抗体 | 7194 |
| 钙卫蛋白单克隆抗体 | 7060 |
| 乳铁蛋白单克隆抗体 | 7343 |
| 转铁蛋白单克隆抗体 | 7341 |
| 血红蛋白单克隆抗体 | 7114 |
| 腺病毒单克隆抗体 | 7299 |
| 轮状病毒单克隆抗体 | 7580 |