Anti-G protein/Gαβγ Recombinant Antibody
- Cat. No.：RB9THX948023
- Price：Negotiable
- Clicks：574
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Clonality | Monoclonal |
| Isotype | scFv-His |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | Crystallography, Cryo-EM |
| Species Reactivity | Homo sapiens (Human) |
| Target | Adenylate cyclase-stimulating G alpha protein, EC:3.6.5.-, GNAS, GNAS1, GSP, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Accession Number | P63092 |
| Background | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gαβγ) is a ~45 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. 1. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 2. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 3. Thiele, S. et al. (2011) Human mutation 32, 653-60. PMID: 21488135 4. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 5. Farfel, Z. et al. (1996) The Journal of biological chemistry 271, 19653-5. PMID: 8702665 6. Warner, DR. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 4268-72. PMID: 10200251 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 6859 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6407 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6901 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6731 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6642 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6404 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6680 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6378 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6259 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6403 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6365 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（6种） | 6546 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6185 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6484 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（8种） | 6584 |
| 单抗融合无忧套装 | 6590 |
| 即用型单抗细胞融合/亚克培养基 | 6343 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6626 |
| 通用型抗体稀释液 | 6263 |
| HRP酶标抗体稀释液 | 6481 |