| Form | Liquid |
|---|---|
| Clonality | Monoclonal |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Species Reactivity | Plasmodium falciparum (isolate 3D7) |
| Target | CS, CSP, Circumsporozoite protein, Circumsporozoite protein C-terminus, PfCSP |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Accession Number | Q7K740 |
| Background | Circumsporozoite protein is a ~42 kDa protein. Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes. 1. Tan, J. et al. (2018) Nature medicine 24, 401-407. PMID: 29554084 2. Oyen, D. et al. (2020) PLoS pathogens 16, e1008373. PMID: 32150583 |
| Note | For research use only |