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Anti-galactose-deficient IgA1 Recombinant Antibody

  • Cat. No.:RB9THV621013
  • Price:Negotiable
  • Clicks:251

Product Detail

Product Parameters

FormLiquid
Host SpeciesRat
ClonalityMonoclonal
IsotypeIgG2b, kappa
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IF, IHC
Species ReactivityHomo sapiens (Human)
Targetgalactose-deficient IgA1, Gd-IgA1, IGHA1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, Immunoglobulin heavy constant alpha 1
Storage Buffer0.01M PBS pH 7.4
Stability and StorageUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
ReconstitutionReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Accession NumberP01876
Background

Immunoglobulin heavy constant alpha 1 (Gd-IgA1) is a ~42 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
4. Kerr, MA. (1990) The Biochemical journal 271, 285-96. PMID: 2241915
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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