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Anti-Human DDX5 Polyclonal Antibody

  • Cat. No.:RB9THA418014
  • Price:Negotiable
  • Clicks:422

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetDDX5, DEAD box protein 5, EC:3.6.4.13, G17P1, HELR, HLR1, Probable ATP-dependent RNA helicase DDX5, RNA helicase p68
ImmunogenE. coli - derived recombinant Human DDX5 (Arg68-Ser483).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP17844
Background

Probable ATP-dependent RNA helicase DDX5 is a ~69 kDa protein. Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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