Anti-Human ATF6 Polyclonal Antibody
- Cat. No.：RB9THB163044
- Price：Negotiable
- Clicks：548
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | ATF6, ATF6-alpha, Activating transcription factor 6 alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transc |
| Immunogen | E. coli - derived recombinant Human ATF6 (Ala547-Gln670). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P18850 |
| Background | Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) is a ~74 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR). 1. Haze, K. et al. (1999) Molecular biology of the cell 10, 3787-99. PMID: 10564271 2. Yoshida, H. et al. (2001) Molecular and cellular biology 21, 1239-48. PMID: 11158310 3. Yoshida, H. et al. (2001) Cell 107, 881-91. PMID: 11779464 |
| Note | For research use only |
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