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Anti-Human ATP6V1C1 Polyclonal Antibody

  • Cat. No.:RB9THB838024
  • Price:Negotiable
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Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetATP6C, ATP6D, ATP6V1C1, V-ATPase subunit C 1, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1
ImmunogenE. coli - derived recombinant Human ATP6V1C1 (Met1-Lys382).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP21283
Background

V-type proton ATPase subunit C 1 (ATP6V1C1) is a ~43 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.

1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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