| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Mouse, Human |
| Target | ATP6C, ATP6D, ATP6V1C1, V-ATPase subunit C 1, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1 |
| Immunogen | E. coli - derived recombinant Human ATP6V1C1 (Met1-Lys382). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P21283 |
| Background | V-type proton ATPase subunit C 1 (ATP6V1C1) is a ~43 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. 1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002 |
| Note | For research use only |