Anti-Human FUT1 Polyclonal Antibody
- Cat. No.：RB9THB940014
- Price：Negotiable
- Clicks：467
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | Alpha(1,2)FT 1, Blood group H alpha 2-fucosyltransferase, EC:2.4.1.344, EC:2.4.1.69, FUT1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Galactoside alpha-(1,2) |
| Immunogen | E. coli - derived recombinant Human FUT1 (Thr80-Pro365). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P19526 |
| Background | Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1) is a ~41 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a. 1. Larsen, RD. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 6674-8. PMID: 2118655 2. Moehler, TM. et al. (2008) Journal of cellular physiology 215, 27-36. PMID: 18205178 |
| Note | For research use only |
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