Anti-Human TUT7 Polyclonal Antibody
- Cat. No.：RB9THC200014
- Price：Negotiable
- Clicks：606
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | EC:2.7.7.52, HS2, KIAA1711, TUT7, TUTase 7, Terminal uridylyltransferase 7, ZCCHC6, Zinc finger CCHC domain-containing protein 6 |
| Immunogen | E. coli - derived recombinant Human TUT7 (Lys996-Arg1379). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q5VYS8 |
| Background | Terminal uridylyltransferase 7 (TUT7) is a ~171 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms. 1. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396 2. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299 3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828 4. Thornton, JE. et al. (2012) RNA (New York, N.Y.) 18, 1875-85. PMID: 22898984 5. Faehnle, CR. et al. (2017) Nature structural & molecular biology 24, 658-665. PMID: 28671666 6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 6834 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6390 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6876 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6719 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6614 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6387 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6658 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6353 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6241 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6386 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6343 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（6种） | 6514 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6164 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6462 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（8种） | 6565 |
| 单抗融合无忧套装 | 6573 |
| 即用型单抗细胞融合/亚克培养基 | 6330 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6607 |
| 通用型抗体稀释液 | 6241 |
| HRP酶标抗体稀释液 | 6461 |