Anti-Human TUT7 Polyclonal Antibody
- Cat. No.：RB9THC200014
- Price：Negotiable
- Clicks：519
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | EC:2.7.7.52, HS2, KIAA1711, TUT7, TUTase 7, Terminal uridylyltransferase 7, ZCCHC6, Zinc finger CCHC domain-containing protein 6 |
| Immunogen | E. coli - derived recombinant Human TUT7 (Lys996-Arg1379). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q5VYS8 |
| Background | Terminal uridylyltransferase 7 (TUT7) is a ~171 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms. 1. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396 2. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299 3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828 4. Thornton, JE. et al. (2012) RNA (New York, N.Y.) 18, 1875-85. PMID: 22898984 5. Faehnle, CR. et al. (2017) Nature structural & molecular biology 24, 658-665. PMID: 28671666 6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 炔诺酮单抗 | 5447 |
| 磺胺氯吡嗪单抗 | 5444 |
| 呋喃苯烯酸钠单抗 | 5356 |
| 呋喃它酮代谢物（2-NPAMOZ）单抗 | 5260 |
| 呋喃西林代谢物（2-NPSEM）单抗 | 5158 |
| 磺胺喹恶啉单抗 | 5408 |
| 苯丙酸诺龙单抗 | 5279 |
| 司帕沙星单抗 | 5127 |
| 妥布霉素单抗 | 5336 |
| 甲氧氯普胺单抗 | 5232 |
| 莫能菌素单抗 | 5356 |
| 多粘菌素B（粘菌素）单抗 | 5682 |
| 磺胺类单抗 | 5446 |
| 托灭酸（托芬那酸）单抗 | 5260 |
| 卡洛芬单抗 | 5247 |
| 喹乙醇代谢物MQCA单抗 | 5339 |
| 氟尼辛单抗 | 5204 |
| 磺胺二甲嘧啶（SM2）单抗 | 5125 |
| 诺龙（19-去甲睾酮）单抗 | 5247 |
| 阿苯达唑-2-氨基砜单抗 | 5193 |