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Anti-Human DESI2 Polyclonal Antibody

  • Cat. No.:RB9THC211014
  • Price:Negotiable
  • Clicks:348

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human, Rat
TargetC1orf121, DESI2, DeSI-2, Desumoylating isopeptidase 2, Deubiquitinase DESI2, EC:3.1.2.22, EC:3.4.19.12, FAM152A, PPPDE peptidase domain-containing protein 1, PPPDE1, Palmitoyl protein thioesterase DES
ImmunogenE. coli - derived recombinant Human DESI2 (Met1-Leu194).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9BSY9
Background

Deubiquitinase DESI2 is a ~21 kDa protein. Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).

1. Xie, X. et al. (2017) Biochemical and biophysical research communications 488, 291-296. PMID: 28483520
2. Luebben, AV. et al. (2022) Science advances 8, eabj8633. PMID: 35427157
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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