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Anti-Human WNT4 Polyclonal Antibody

  • Cat. No.:RB9THC249014
  • Price:Negotiable
  • Clicks:128

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Rat, Human
TargetProtein Wnt-4, WNT4
ImmunogenE. coli - derived recombinant Human WNT4 (Ser23-Arg351).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP56705
Background

Protein Wnt-4 (WNT4) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung. Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development. Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries.

1. Biason-Lauber, A. et al. (2004) The New England journal of medicine 351, 792-8. PMID: 15317892
2. Biason-Lauber, A. et al. (2007) Human reproduction (Oxford, England) 22, 224-9. PMID: 16959810
3. Mandel, H. et al. (2008) American journal of human genetics 82, 39-47. PMID: 18179883
4. Philibert, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 895-900. PMID: 18182450
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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