| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Rat, Human |
| Target | Protein Wnt-4, WNT4 |
| Immunogen | E. coli - derived recombinant Human WNT4 (Ser23-Arg351). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P56705 |
| Background | Protein Wnt-4 (WNT4) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung. Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development. Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries. 1. Biason-Lauber, A. et al. (2004) The New England journal of medicine 351, 792-8. PMID: 15317892 2. Biason-Lauber, A. et al. (2007) Human reproduction (Oxford, England) 22, 224-9. PMID: 16959810 3. Mandel, H. et al. (2008) American journal of human genetics 82, 39-47. PMID: 18179883 4. Philibert, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 895-900. PMID: 18182450 |
| Note | For research use only |